The chloroform extract of the leaves of Caesalpinia pyramidalis (Caesalpinioidea , Fabaceae) yielded the new biflavonoid named caesalflavone, as well as. Recebido em 17/9/09; aceito em 2/2/10; publicado na web em 18/6/10 The chloroform partition of methanol extract of leaves of Caesalpinia. PDF | The chloroform extract of the leaves of Caesalpinia pyramidalis ( Caesalpinioidea, Fabaceae) yielded the new biflavonoid named caesalflavone, as well as.
|Published (Last):||6 March 2011|
|PDF File Size:||11.54 Mb|
|ePub File Size:||6.12 Mb|
|Price:||Free* [*Free Regsitration Required]|
Biflavonoids were not found in trunk wood. Evidence-Based Complementary and Alternative Medicine. There are several species of plants used by traditional communities in the Brazilian semiarid. On the other hand, the bonded hydroxyl d For leukocyte counts, similar results were observed in the posttreatment groups and also no significant differences were seen in the eosinophil values in blood when compared to the negative and positive control. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.
FEC determination was carried out in four regular intervals, initially, two weeks before assay, with the aim at tracing vaesalpinia randomly distributing the animals into four groups at day zero, prior treatment extract and doramectinand then at days 30 and 60 after treatment in all groups.
The anthelmintic doramectin and the extract were administered through three consecutive days from the time zero.
Parasitological and Zootechnical Measures FEC determination was carried out in four regular intervals, initially, two weeks before assay, with the aim at tracing and randomly caesalpiniw the animals into four groups at day zero, prior treatment extract and doramectinand then at days 30 and 60 after treatment in all groups.
On the other hand, the flavanone unit was recognized by caesalpihia characteristic 13 C signals, which were attributed to a carbonyl group as well as to the C-2 and oxybenzylic carbon of ring C.
Goat herding is an attractive source of income for farmers in northeastern Brazil. The 1 H NMR spectrum of 1 also corroborated to propose the biflavonoid structure and the linkage between the flavanone and flavone units. The correlation of H-8 and C of unity I was conclusive to identify this unit as being the flavone linked with C-3′ of the flavanone unit II Figure 2. The genus Caesalpinia Fabaceaecomposed of tropical or subtropical pyramidals and shrubs, contains more than species, spread throughout the world [ 7 ].
A possible explanation of this reduction may be due to the direct effect of CP extract on parasite leading to drop in FEC in natural infected goats.
All these parameters are considered to be important element in the response against GIN infection. In the present experiment, it is likely that another mechanism of the CP extract affects against GIN. For these various reasons, interest in the plant screening for their anthelmintic activity remains of great scientific interest despite extensive use of synthetic chemicals in modern clinical practices all over the world as an alternative source of anthelmintics [ 4 — 6 ].
To receive news and publication updates for Evidence-Based Complementary and Alternative Medicine, enter your email phramidalis in the box below. Nova27 Despite a significant decline in mean FEC, blood parameters did not change significantly throughout the experiment between any groups.
The average values were not significantly different between the extract and Doromectin treated groups G2, G3, G4 and the untreated group G1.
Evidence-Based Complementary and Alternative Medicine
The HMQC spectrum was elucidative pyramidails it was possible to verify the correlations of two hydrogen signals and two carbon resonances each. Dosage standard curves were obtained following the protocols provided by the manufacturer. Phenolic compounds were also evaluated in vitro for their antimicrobial activity to control pathogenic bacteria [ 41727 ].
This response could be partly explained by the CP chemical composition. Comparison with literature data 9 permitted to re-assign some peaks.
In addition, should be considered the differences between animals and their susceptibility to nematode infection [ 1516 ].
Caesalpinia pyramidalis – Wikipedia
The absence of bathochromic effect permitted to localize the methoxyl group in the C-2′. Some compounds from C. The egg excretion pattern was caesalpnia for the positive control G2 and treated groups G3 and G4.
Introduction Goat herding is an attractive source of income for farmers in northeastern Brazil. June 10, Published on the web: Botanical material of C. Similarly, the extract does not appear to have influenced the change of weight in animal groups during the experimental period. The chloroform extract Biflavonoids and other phenolics from Caesalpinia pyramidalis Fabaceae. Thus, the observed FEC reduction in this work is consistent with other studies that have reported that plant extracts rich in polyphenolic compounds induced anthelmintic activity, involving experimental animals that have been used in trials to validate medicinal activities [ 9101318 ].
Dry trunk wood 5. Animals were weighed average weight before starting the trial G1: From the chloroform extract trunk wood were obtained the known compounds 4,4′-dihydroxy-2′-methoxychalcone 4syringaresinol 5and methyl gallate. Moreover, the serum anti- Haemonchus antibody responses presented significant increases in G2 and G3, whereas G4 yielded an average OD of 1.
The chloroform partition In addition, serum IgA levels had a significant response in the 5. In the study of humoral immune response, antibodies of two immunoglobulin classes were investigated: Van Leeuwen, and W. Probably the higher deviations on the determined FEC values were due to the traditional and extensive management practices in the Brazilian semiarid region; therefore, the goats were always exposed pyrammidalis a contaminated environment.
Biflavonoids and other phenolics from Caesalpinia pyramidalis (Fabaceae)
The mechanisms whereby the consumption of certain plants and plant extracts can affect parasite cycle both in vitro and in vivo are unknown. Once some plants have been reported caealpinia have anthelmintic properties, attributed to secondary metabolites e. The antiulcer assays were performed using the ethanol- and nonsteroidal anti-inflammatory drug-induced ulcer models. Abstract Forty-eight goats naturally infected with gastrointestinal nematodes were randomly divided into four groups: