Si bien la leucemia linfoblástica aguda puede presentarse a cualquier edad, es el tipo de cáncer que se encuentra más comúnmente en niños y adultos. Antecedentes: la bibliografía estadounidense reporta leucemia linfoblástica aguda hiperdiploide en 30% de los casos en niños. Se han encontrado diferencias. Evolución de la leucemia linfoblástica aguda en la edad pediátrica en 29 años . preliminaries del tratamiento de la leucemia linfoblástica en el niño en Cuba.

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Medical and Pediatric Oncology ; Cancer ; 3: Am J Hum Genet ; Lippincott Williams and Wilkins, ; Prognosis of Down’s syndrome with acute leukaemia. Biology and clinical significance of cytogenetic abnormalities in childhood acute lymphoblastic leukemia. The relapse rate was not increased, if compared with non DS ALL patients; in this group the infections were the determinant factor for a lower survival.


Pediatr Blood Cancer ; The group of patients with Niod and DS evaluated was not associated with classic treatment resistance linfoblatsica.

¿Cómo se clasifica la leucemia en niños?

Down syndrome and acute leukemia in children: Cytogenetic and molecular studies of Down syndrome individuals with leukemia. These patients can be treated with the current trials but they require a detailed infection care. Abnormal serum IgG subclass pattern in children with Down’s syndrome.

J Pediatr Hematol Oncol ; Estos pacientes pueden ser tratados con los protocolos actuales pero requieren un manejo precoz e intensivo de las infecciones. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia Blood and Cancer ; Rev Chil Pediatr ; 83 1: Pediatr Clin North Am ; Proposal for the immunological classification of acute leukemias.

Clonal hematologic disorders in Down syndrome. J Pediatr ; Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia.


Leucemia linfoblástica aguda en pacientes portadores de síndrome de Down

Immunology of Down syndrome. Acute lymphoblastic leukemia and Down syndrome: Insights into the manifestations, outcomes, and mechanisms of leuke mogenesis in Down syndrome. Hospital Regional Valdivia, Drs: Hospital Luis Calvo Mackenna, Drs: Hospital San Borja, Drs: Clinical characteristics and treatment outcome of children with acute lymphocytic leukemia and Down’s syndrome.

Hospital Regional de Antofagasta, Dr. Leukemia in Down syndrome. Clinical and biological characteristics of acute lymphocytic leukemia in children with Down syndrome.

Principles and practice of pediatric oncology 4 th Edition Philadelphia.